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禽用活疫苗外源病毒污染的摸底调查
刘丹、侯力丹,李启红,黄小洁,李俊平,杨承槐
0
(中国兽医药品监察所)
摘要:
为对禽用活疫苗污染外源病毒的情况进行彻底摸底调查,我们抽取了目前使用量大、覆盖面广的禽用活疫苗重点品种共8种28批,涉及18家国内生产企业、7家国外企业,疫苗生产用SPF鸡胚来自国内8家企业。按照《中国兽药典》2010年版三部鸡检查法和《禽病活疫苗禽腺病毒污染摸底调查工作方案》对抽检的禽病活疫苗进行了外源病毒污染和禽腺病毒污染检验。结果显示所抽检的禽用活疫苗均无外源病毒污染和禽腺病毒污染,表明我国禽用活疫苗的质量控制和安全性良好。
关键词:  禽用活疫苗  外源病毒  腺病毒  污染
DOI:
投稿时间:2017-05-31修订日期:2017-06-29
基金项目:
The Investigation into the Extraneous Virus Contaminations of the Avian Live vaccines
(China Institute of Veterinary Drug Control)
Abstract:
In order to investigate the extraneous virus contaminations of the avian live vaccines, we extracted the avian live vaccines which were widely used and covered, involving 18 domestic production enterprises, 7 foreign enterprises, the SPF chicken embryo used for the vaccine production were came from eight domestic enterprises. According to chicken test of the veterinary pharmacopoeia of the people" republic of china (2010) and 《Investigation plan into the group I adenovirus contaminations of the avian live vaccines》, the common extraneous viruses and group I adenovirus were tested. The results showed that the 28 batches avian live vaccines were not contaminated with extraneous viruses and group I adenovirus, indicating the quality control and safety of the avian live vaccines were good.
Key words:  Avian Live vaccines  Extraneous Virus  group I adenovirus  Contamination

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